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・ YOP
・ Yop
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・ YopE protein domain
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・ YopH, N-terminal
・ Yoplait
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YopR bacterial protein domain
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・ Yor-yor (film)
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YopR bacterial protein domain : ウィキペディア英語版
YopR bacterial protein domain

In molecular biology, YopR is a protein domain commonly found in gram negative bacteria, in particular ''Yersinia'' and is a core domain. Proteins in this entry are type III secretion system effectors. They are named differently in different species and in ''Yersinia'' has been designated YopR (Yersinia outer protein R) which is encoded by the YscH (Yersinia secretion H) gene. This Yop protein is unusual in that it is released to the extracellular environment rather than injected directly into the target cell as are most Yop proteins.
A hallmark of ''Yersinia'' type III machines is the presence of needles extending from the bacterial surface. Needles perform two functions, firstly, as a channel to export effectors into the immune cells and secondly as a sensor.
==Function==
In summary, YopR may play a role in the regulation of type III secretion. It is important to note, however, that the precise function of the YopR domain remains to be elucidated but YopR is thought to be involved in with YscF which develops needles. There are two different hypotheses for this. The first explanation is that YopR is possibly controlling the secretion of YscF, which impacts the assembly of type III machines. Alternatively, it is thought that YopR directly polymerizes YscF; this explanation is thought to be less likely since YopR does not associated with purified needles.〔

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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